Journal Articles

The following articles acknowledge the support of the Liddy Shriver Sarcoma Initiative.

Annual Review of Pathology
Mouse Models of Cancer

Genetic amplification of the vascular endothelial growth factor (VEGF) pathway genes, including VEGFA, in human osteosarcoma

Cancer Letters
Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma

Cancer Research
A Role for BRCA1 in Uterine Leiomyosarcoma

EWS/FLI and Its Downstream Target NR0B1 Interact Directly to Modulate Transcription and Oncogenesis in Ewing's Sarcoma

Histone H2AX Is a Mediator of Gastrointestinal Stromal Tumor Cell Apoptosis following Treatment with Imatinib Mesylate

Clinical Cancer Research
Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment

Current Cancer Drug Targets
Inhibition of Cdc42-Interacting Protein 4 (CIP4) Impairs Osteosarcoma Tumor Progression

Current Opinion in Genetics & Development
Pediatric malignancies: update on sarcomas and leukemia development in children

Frontiers in Oncology
Human Rhabdomyosarcoma Cell Lines for Rhabdomyosarcoma Research: Utility and Pitfalls

Genes & Cancer
Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing’s Sarcoma

Journal of Clinical Investigation
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression

CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

Journal of Oncology
Is There a Predisposition Gene for Ewing's Sarcoma?

Journal of Surgical Research
Antitumor activity of polyuridylic acid in human soft tissue and bone sarcomas

Lab Investigations
An experimental model for the study of well-differentiated and dedifferentiated liposarcoma

Molecular Cancer Therapeutics
NF1 Deletion Generates Multiple Subtypes of Soft-Tissue Sarcoma That Respond to MEK Inhibition

Nature Genetics
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome 

Nature Medicine
A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing’s sarcoma

CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity

GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistanceGSTM4 in Ewing's sarcoma

miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells

Proceedings of the National Academy of Sciences of the United States of America
Microsatellites as EWS/FLI response elements in Ewing’s sarcoma

Cell Cycle Deregulation in Ewing’s Sarcoma Pathogenesis

Seminars in Oncology
Small Round Cell Sarcomas

Technology in Cancer Research and Treatment
APEX1 gene amplification and its protein overexpression in osteosarcoma: correlation with recurrence, metastasis, and survival