A Periodical for the Sarcoma Community

January 2014 - Volume 11, Number 1

Diagnosing Sarcomas

Editorial by Bruce Shriver, PhD

Opinions and Hypotheses

2014: The Year of Immunotherapy in Sarcoma?

Drs. Seth Pollack and Robin Jones make the case for an intentional focus on advancing immunotherapy for sarcomas.

Personalized Medicine: Continuing the Discussion

Drs. Fletcher and Thomas write about hope, optimism and the scientific limits that impact oncologists and sarcoma patients.

Feature Articles

Mechanisms of EWS/FLI1-GLI1 Activation in Ewing Sarcoma

Experimental Plan: Dr. William A. May describes his study of the interaction between EWS/FLI1 and GLI1 in Ewing's sarcoma.

Mutation Profiling in Uterine Carcinosarcoma (MMMT)

Study Report: Ms. McConechy and Drs. Huntsman, Lee, and Clarke report their findings on the transdifferentiation of uterine carcinoma into sarcoma and the frequent PI3K pathway mutations in uterine carcinosarcoma.

Anti-PD1 Therapy for Pediatric Sarcomas

Study Report: Drs. Highfill, Orentas, and Mackall write about their findings on immunotherapy for pediatric sarcomas and their research approach moving forward.


Additions to the Initiative's Medical Advisory and Editorial Board

The Initiative is pleased to announce that Dr. Judith Bovée and Dr. Alexander Lazar have joined our Medical Advisory and Editorial Board.

$50,000 Grant Funds Study on Hedgehog-GLI Signaling in Ewing's Sarcoma

The Brian Morden Foundation and the Liddy Shriver Sarcoma Initiative are co-funding a grant for Ewing's sarcoma research in Los Angeles.

Translated Articles

Sarcoma Radio-Indotto dei Tessuti Molli

Marilena Cesari, MD provides an Italian translation of the ESUN review article on radiation-induced sarcomas.


Keisuke Akaike, MD and Yoshiyuki Suehara, MD, PhD provide a Japanese translation of the ESUN review article on radiation-induced sarcomas.