ESUN

A Periodical for the Sarcoma Community

August 2012 - Volume 9, Number 4

Working Together to Advance Sarcoma Research

Editorial by Bruce Shriver, PhD

miRNA Alterations in Leiomyosarcoma Pathogenesis

In this study report, Laura Danielson, PhD and Eva Hernando, PhD describe their findings which they believe place miR-130b as an important factor that may contribute to the undifferentiated nature of LMS and regulate its ability to migrate and invade.

Exploitation of the Mammalian Hippo Pathway and its Members in the Treatment of Alveolar Rhabdomyosarcoma

In this experimental plan, Lisa Crose, PhD and Corinne Linardic MD, PhD describe their plan to identify Hippo pathway regulators important in Alveolar Rhabdomyosarcoma and to provide a platform for designing new mouse models and therapeutic approaches.

ROCK Inhibition as an Anti-Angiosarcoma Therapeutic

In this experimental plan, Brad A. Bryan, PhD describes a study intended to shed light on the molecular roles of ROCK proteins in angiosarcoma tumor formation and establish a therapeutic foundation for what appears to be an excellent anti-angiosarcoma target.

Announcements

$50,000 Rhabdomyosarcoma Research Grant Awarded

The Initiative has awarded a $50,000 research study on Rhabdomyosarcoma at Duke University Medical Center.

$45,000 Angiosarcoma Research Grant Awarded

The Initiative has awarded a $45,000 research study on Angiosarcoma at Texas Tech University Health Sciences Center.

The Survivors Project

We will begin publishing the powerful stories of sarcoma survivors in the next issue of ESUN! Please share your story.

Translated Articles

软组织透明细胞肉瘤 (Clear Cell Sarcoma)

Dr. Yang provide a Chinese translation of the ESUN review article about Clear Cell Sarcoma.

Sarcome Alvéolaire des Tissus Mous

Dr. Dutor provides a French translation of the ESUN review article about Alveolar Soft Part Sarcoma.

Sarcoma Alveolar de Partes Blandas (SAPB)

Dr. González provides a Spanish translation of the ESUN review article about Alveolar Soft Part Sarcoma.