A Periodical for the Sarcoma Community

February 2010 - Volume 7, Number 1

The International Sarcoma Awareness Week: July 17-25, 2010

Editorial by Bruce Shriver, PhD

Desmoplastic Small Round Cell Tumor: A Review

Fernanda Arnaldez, MD and David Loeb, MD, PhD review the clinical manifestations, diagnosis, pathological findings, molecular analysis and treatment of DSRCT.

The Role of Cytoplasmic p27kip1 in Metastatic Osteosarcoma

In this experimental plan, Yiting Li., MD, PhD and Tsz-Kwong Man, PhD discuss the role of p27kip1 in metastatic osteosarcoma and its relationship with the mTOR pathway.

High throughput miRNA expression profiling for well differentiated and de-differentiated liposarcoma: a progress report

In this study report, Dina Lev, MD discusses why additional molecular alterations/dysregulations are necessary to account for the dismal prognosis of dedifferentiated liposarcomas.

A Mouse Model of Chordoma

In this study report, Brian Harfe, PhD discusses why the presence of limb defects in the mice he is studying suggests the Shh signaling pathway has been activated in notochordal remnants.


$50,000 Grant for Osteosarcoma Research Awarded

The Liddy Shriver Sarcoma Initiative awards a $50,000 grant for research in the Department of Pediatrics at Baylor College of Medicine.